产品货号：
Z39514
中文名称：
PTP1B/PTPN1抗体
英文名称：
Anti-PTP1B/PTPN1 Antibody
产品规格：
50μL|100μL|150μL
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PTP1B/PTPN1 Antibody |
| 指标别名 | PTP 1B;PTP1B;PTPN1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | PTPN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human PTP1B |
| 实际分子量 | 50KD |
| 成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family,which was isolated and identified based on its enzymatic activity and amino acid sequence.PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues.Members of the PTP family share a highly conserved catalytic motif,which is essential for the catalytic activity.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,differentiation,mitotic cycle,and oncogenic transformation.This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase.This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase,as well as JAK2 and TYK2 kinases,which implicated the role of this PTP in cell growth control,and cell response to interferon stimulation.Two transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | PTPN1:P18031 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:20～100 ImmunoPrecipitation (IP) 1:20 |
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